Modulating immune responses by targeting dendritic cells using dendritic cell specific markers. [ 2005 - 2005 ]

Research Grant

Researchers: Prof Ken Shortman (Principal investigator) ,  A/Pr Irina Caminschi ,  A/Pr Mireille Lahoud ,  Prof Andrew Lew

Brief description The ability to modulate immune responses would have major health benefits. Dendritic cells (DC) are key regulators of the immune system. Different types of DC possess different cell surface molecules and have differing regulatory functions. We have identified four novel DC surface molecules that can be used to target different types of DC. We aim to use antibodies against these molecules to either enhance the effectiveness of vaccines or to suppress autoimmune diseases.

Funding Amount $AUD 197,750.00

Funding Scheme NHMRC Development Grants

Notes Development Grant