Modafinil for neurobehavioural dysfunction in sleep apnea patients who cannot use standard device-based treatments. [ 2011 - 2015 ]

Research Grant

Researchers: A/Pr Nathaniel Marshall (Principal investigator) ,  A/Pr Brendon Yee ,  A/Pr Keith Wong ,  Prof Ronald Grunstein

Brief description Obstructive sleep apnea (OSA) is often caused by obesity and can result in fall-asleep car crashes. It is often treated by mechanical devices that keep the sleeping airway open. Unfortunately, around half of all patients cannot tolerate these treatments. We propose to help patients reduce obesity with a lifestyle intervention program whilst testing whether their daytime symptoms of sleepiness and poor driving ability can be treated with a wake-promoting drug called modafinil.

Funding Amount $AUD 505,830.24

Funding Scheme Project Grants

Notes Standard Project Grant