grant

MLKL-regulated necroptosis pathways in disease [ 2014 - 2017 ]

Also known as: Detailed analysis of an emergent cell death pathway

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1057905]

Researchers: A/Pr James Murphy (Principal investigator) ,  Dr Isabelle Lucet Prof John Silke

Brief description Only recently has it emerged that our cells have a built-in backup mechanism that instructs cells to die in extreme cases, such as when viruses have hijacked a cell. A misfiring backup mechanism is thought to underlie a number of human diseases, including inflammatory disease. Our investigation will establish a starting point for the development of novel anti-inflammatory drugs.

Funding Amount $AUD 610,683.17

Funding Scheme Project Grants

Notes Standard Project Grant

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