Mitochondrial ribosomal pentatricopeptide domain proteins regulate protein synthesis in health and disease [ 2011 - 2013 ]

Research Grant

Researchers: A/Pr Oliver Rackham (Principal investigator) ,  A/Pr Aleksandra Filipovska ,  Prof Ian Small ,  Prof James Whelan

Brief description Mitochondria in our cells regulate energy production from food and play an important role in health and disease. Defects in mitochondrial protein synthesis lead to severe neurodegenerative and sensory diseases and may contribute to cancer and ageing. This research aims to investigate the role of mitochondrial proteins that regulate translation in mitochondrial diseases. Characterisation of these proteins provides an unexplored resource of potential disease modulators and drug targets.

Funding Amount $AUD 444,108.95

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant