The missing link: mGluR5 as a therapeutic target for cognitive decline in dementia [ 2016 - ]

Research Grant

Researchers: Dr Emma Burrows (Principal investigator)

Brief description Cognitive decline is a core feature of Alzheimer’s Disease (AD), yet there is no cure or treatment. Recent evidence suggests that a protein called mGluR5 could cause brain cells to lose function, leading to memory loss. This project will investigate whether disrupting mGluR5 function can improve cognition in mice with genetic AD. Memory will be assessed in mice using innovative touchscreen tests that closely mimic the tests used in humans.

Funding Amount $563,622.00

Funding Scheme Boosting Dementia Research Initiative

Notes NHMRC - ARC Dementia Research Development Fellowship