Mineralocortioid Receptor-Mediated Injury in Progressive Kidney Disease [ 2016 - ]

Research Grant

Researchers: A/Pr Greg Tesch (Principal investigator) ,  A/Pr David Nikolic-Paterson ,  Dr Morag Young

Brief description Diabetes is the major cause of kidney failure. Activation of a hormone receptor (the mineralocorticoid receptor-MR) can promote kidney injury. Current drugs blocking MR can suppress diabetic kidney disease but are limited by their poor specificity and harmful side effects. Our study will help improve strategies for blocking MR by identifying the cell types responsible for MR-mediated injury and by examining whether a new class of drug targeting MR is a superior therapy to current MR inhibitors.

Funding Amount $707,008.00

Funding Scheme Project Grants

Notes Standard Project Grant