grant

microRNA dysregulation as a mechanism underlying muscle wasting [ 2010 - 2012 ]

Also known as: Does microRNA mis-expression contribute to muscle wasting?

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/586649]

Researchers: A/Pr Paul Gregorevic (Principal investigator) ,  A/Pr Izhak Haviv Prof Lars Larsson

Brief description Frailty caused by muscle wasting shortens many peoples' lives and costs hundreds of billions of dollars in care and lost productivity annually. In the hope of finding ways to treat frailty, we will study whether naturally-occurring microRNA molecules are responsible for disrupting gene expression to cause muscle disease. We will identify which types of microRNA are altered in muscle diseases, and test whether adjusting microRNA levels with new approaches can prevent-treat muscle wasting.

Funding Amount $AUD 514,454.96

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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