Microparticles are pathogenic elements in the pathophysiology of cerebral malaria [ 2012 - 2014 ]

Research Grant

Researchers: Dr Valery Combes (Principal investigator) ,  Dr Julie Wheway ,  Prof Georges Grau

Brief description Cerebral malaria (CM) is still a world health problem. We aim to better understand its mechanisms by deciphering the role of small blood elements called microparticles (MP). We discovered elevated numbers of MP in CM patients and demonstrated that preventing MP overproduction in mice protects against this fatal disease. Our research will investigate the mechanisms of action and the fate of MP in the blood vessels during CM and allow us to identify strategies for patientÍs treatment and care.

Funding Amount $AUD 605,205.86

Funding Scheme Project Grants

Notes Standard Project Grant