The Microniche: A novel in-vitro and in-vivo prostate cancer model system [ 2016 - ]

Research Grant

Researchers: A/Pr Michael Doran (Principal investigator) ,  Dr Brian Tse ,  Dr Ian Vela ,  Prof Pamela Russell

Brief description Maintaining primary prostate cancer cells (PCa) in vitro remains an enormous challenge for the field, and this obstructs efforts to systematically characterize cell behaviour and quantify drug response. Our group recently developed a 3-demsensional (3D) organoid culture system that does maintain PCa in vitro, and here we will integrate this technology with our 3D bone maorrow niche model system to better characterize PCa bone metastases and identify new clinical treatment regimes.

Funding Amount $561,012.00

Funding Scheme Project Grants

Notes Standard Project Grant