Microglial paralysis in post-stroke neurodegeneration: help or hindrance? [ 2018 - ]

Research Grant

Researchers: A/Pr Frederick Walker (Principal investigator) ,  Prof Michael Nilsson ,  Prof Neil Spratt

Brief description Dementia and cognitive decline may occur months or years after a stroke, associated with delayed loss of brain cells in different brain regions. We recently discovered that the cells responsible for protection and repair of brain, called microglia, become paralysed in these regions. We will use a live-imaging microscope to determine whether the microglial paralysis causes brain cell death. We will also determine if a commonly used stroke prevention drug can worsen the microglial paralysis.

Funding Amount $512,351.00

Funding Scheme Project Grants

Notes Standard Project Grant