Microenvironmentally Induced Acute Lymphoblastic Leukemia Cell Quiescence and Chemotherapy Evasion [ 2013 - 2016 ]

Research Grant

Researchers: A/Pr Linda Bendall (Principal investigator) ,  A/Pr Louise Purton ,  A/Pr Rosemary Sutton

Brief description Although almost all patients with ALL achieve a remission, a proportion of children and the majority of adults relapse following treatment. Relapse occurs as a result of a small number of malignant cells that survive chemotherapy. We have identified a population of quiescent cells that could represent this population. We believe this population is defined by its location in the bone marrow. This project will characterize this population and determine whether it is protected from chemotherapy.

Funding Amount $AUD 672,885.92

Funding Scheme Project Grants

Notes Standard Project Grant