Microenvironmental regulation of blood cells by retinoic acid receptor gamma. [ 2017 - ]

Research Grant

Researchers: A/Pr Louise Purton (Principal investigator) ,  A/Pr Carl Walkley ,  Dr Alistair Chalk

Brief description Vitamin A deficiency causes profound effects in humans, with anaemia and an inability to fight infection being consequences of vitamin A deficiency on blood cells. We have evidence that these effects of vitamin A deficiency occur via one of the receptors for vitamin A. Furthermore, these effects are due to changes in the non-blood cells that help to make blood cells. By understanding how this occurs we may identify better treatments for patients with impaired immune systems.

Funding Amount $958,428.00

Funding Scheme Project Grants

Notes Standard Project Grant