METHODS - A randomised controlled trial of METhotrexate to treat Hand Osteoarthritis with Synovitis [ 2017 - 2020 ]

Research Grant

Researchers: Dr Andrew Teichtahl (Principal investigator) ,  Dr Helen Keen ,  Dr Yuanyuan Wang ,  Prof Flavia Cicuttini ,  Prof Graeme Jones

Brief description Hand osteoarthritis (OA) is common, but has no treatment. Almost 50% of people with hand OA will have joint swelling (synovitis). The hand joint of people with synovitis are 3.5 times more likely to experience joint destruction within as little as 2 years. Drugs used to treat synovitis may reduce pain and joint destruction. We propose that treating patients with symptomatic hand OA and synovitis with the anti-synovitis drug, methotrexate, will be a major medical advance.

Funding Amount $AUD 788,522.89

Funding Scheme Project Grants

Notes Standard Project Grant