Metagenomics Sequencing Data related to article "Translocation and dissemination of commensal bacteria in post-stroke infection"

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Two pieces of sequencing data under the accession codes 4675190.3 and 4707925.3 are held at the MG-RAST Metagenomics Analysis Server Synopsis of related article is below: Bacterial pneumonia is highly prevalent in stroke patients, and it is widely believed that overt of micro-aspiration is the primary cause of pneumonia among stroke patients. In this study, we demonstrated that post-stroke infection was only observed in mice raised in specific pathogen free (SPF) facilities, and not germ free (GF). We used high throughput 16S rRNA gene amplicon sequencing and relevant bioinformatics tools to determine that the likely sources of bacteria that form the microbial community in the post-stroke lung are the commensal species from the host small intestine. The peripheral dissemination of bacteria inoculated orally was only seen in post-stroke mice. Our results therefore provide evidence to indicate that bacterial infections following stroke are likely to originate endogenously from the host commensal microbiota. Submitted is Qiime processed split library fasta file with all samples strting with S being sham and with T stroke mice.