Metabolically Reprogramming the Stroma to Starve Pancreatic Tumours [ 2018 - 2020 ]

Research Grant

Researchers: A/Pr Phoebe Phillips (Principal investigator) ,  A/Pr Jeffrey Holst ,  Dr Jennifer Morton ,  Dr Joshua Mccarroll ,  Prof David Goldstein

Brief description Pancreatic cancer claims five Australian lives every day. Despite aggressive treatment regimes, there has been no improvement in patient survival in the last decade. Evidence suggests that targeting cancer cells alone is not enough. Pancreatic tumours are surrounded by an extensive scar tissue reaction (stroma). This intense stromal reaction inhibits drug delivery and increases tumour growth. Thus, decreasing the stroma is a potential therapeutic strategy and is the focus of this proposal.

Funding Amount $AUD 607,231.86

Funding Scheme Project Grants

Notes Standard Project Grant