Metabolic wiring in adipocytes - unique role in maintaining long-term health [ 2015 - ]

Research Grant

Researchers: Prof David James (Principal investigator) ,  Prof Gregory Cooney

Brief description Fat cell metabolism is wired to optimize the cell’s ability to make and store lipid while programming the cell to fulfil its function in whole body metabolism. We will: 1) map fat cell metabolism under optimal and insulin resistant conditions; 2) explore the role of 3 nodes in his metabolic circuit predicted as control points; 3) use a novel genetically engineered mouse model to explore the functional significance of fat cell metabolism in whole body insulin sensitivity.

Funding Amount $1,036,222.00

Funding Scheme Project Grants

Notes Standard Project Grant