Mesenchymal Stem Cell maintenance and recruitment during skeletal repair are dependent on EphB-ephrinB signalling [ 2012 - 2014 ]

Research Grant

Researchers: Prof Stan Gronthos (Principal investigator) ,  Prof Andrew Zannettino

Brief description There is currently a steady increase in surgical intervention and rehabilitation therapy for bone related fractures due to trauma or osteoporosis as a consequence of an aging population. Bone regeneration involves the coordinated participation of skeletal precursor cells, blood vessels and immune cells recruited from the surrounding tissues. This proposal examines the mechanisms mediating the maintenance and recruitment of skeletal precursor cells to sites of bone damage.

Funding Amount $AUD 611,827.50

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant