Mesenchymal Progenitor cells and intervertebral disc repair [ 2011 - 2014 ]

Research Grant

Researchers: Dr James Melrose (Principal investigator) ,  Dr Richard Appleyard ,  Prof Christopher Little

Brief description Low back pain affects 80% of the general population and is a major social and economic burden thus there is a clear need for effective treatment. Annual direct and indirect costs for low back pain exceeded $100 billion in the USA in 2006. We will use bone marrow derived multipotent progenitor cells in a regenerative strategy to undertake repair of the intervertebral disc in an ovine mechanical destabilisation model which reproduces early degenerative changes similar to those evident in man.

Funding Amount $AUD 754,223.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant