Menstrual fluid factors in the control of progestin mediated endometrial bleeding [ 2013 - 2015 ]

Research Grant

Researchers: Prof Lois Salamonsen (Principal investigator) ,  Dr Jemma Evans

Brief description Uterine bleeding associated with progestin-only contraceptives is the main reason for discontinuation of these highly effective items. For bleeding to occur the endometrial blood vessels and overlying epithelium must undergo simultaneous breakdown. We do not know the mechanism behind breakdown under progestin exposure. We propose novel directions to understand the molecular cues underlying epithelial fragility/breakdown and novel treatments to stop bleeding thus enhancing contraceptive compliance.

Funding Amount $AUD 379,845.47

Funding Scheme Project Grants

Notes Standard Project Grant