Memory CD4 T cells that harbour the reservoir of latent HIV infection: their antigen specificity, function and frequency of antigen-driven reactivation [ 2011 - 2014 ]

Research Grant

Researchers: Dr John Zaunders (Principal investigator) ,  Dr Kersten Koelsch

Brief description Current antiretroviral therapy for HIV successfully suppresses virus production, but does not completely eliminate the virus from the body. This project will provide essential information on memory CD4 T cells that retain HIV in a latent DNA form. Memory CD4 T cells can be very long-lived, and these latently infected memory cells can give rise to virus during treatment interruption. We will use a novel method to identify which memory CD4 T cells contain latent HIV DNA.

Funding Amount $AUD 453,782.24

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant