Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/545918]Researchers: Prof Iain Clarke (Principal investigator) , Prof Alexander Smith
Brief description Reproduction is controlled by the brain through the hormone gonadotropin releasing hormone (GnRH). Leptin from fat acts on the brain to 'inform' GnRH cells of metabolic state; low levels signal lack of energy stores and suppress reproduction. Leptin treatment of lean individuals restores reproductive function, but the mechanism is not clear. Our data implicate the melanocortins as a means of transmitting information on metabolic state to GnRH cells and the project investigates this pathway.
Funding Amount $AUD 591,967.89
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 545918
- PURL : https://purl.org/au-research/grants/nhmrc/545918
