A mechanotransduction apparatus to coordinate epithelial collective cell migration. [ 2017 - 2020 ]

Research Grant

Researchers: Prof Alpha Yap (Principal investigator)

Brief description Epithelial cells migrate as physically coherent collective groups, which is necessary for normal development and is disrupted as cancers progress to become invasive and spread. Collective migration requires communication so that the behaviour of individual cells is properly coordinated. In this project we investigate how the transmission of physical force between cells allows them to communicate; and test how its disruption contributes to cancer invasion.

Funding Amount $AUD 1,019,003.35

Funding Scheme Project Grants

Notes Standard Project Grant