grant

Mechanosensitive channels: Antimicrobials, channelopathies and nanovalves for drug delivery [ 2010 - 2012 ]

Also known as: Optimization of Targeted Drug Delivery

Funded by National Health and Medical Research Council
Managed by Victor Chang Cardiac Research Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/635513]

Researchers: Prof Boris Martinac (Principal investigator) ,  Prof Ben Hankamer

Brief description Liposomal drug delivery systems (LDDS) are one of the most advanced particulate drug carriers in modern medicine. The ultimate goal of this project is to optimize a nanotechnology approach for improved control of therapeutic drug delivery for chemotherapy. The approach is using bacterial mechanosensitive channel MscL designed to act as a molecular nanovalve for localised drug release.

Funding Amount $AUD 673,953.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Antimicrobials | Cancer chemotherapy | Channelopathies | Drug delivery systems | Electron microscopy | Ion channels | Lipid bilayers | Lipids | Nanotechnology | Nanobiotechnology | Patch clamping | Protein structure | Technology |
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