grant

MECHANISTIC ROLE OF CHOLESTEROL IN NON-ALCOHOLIC STEATOHEPATITIS [ 2010 - 2013 ]

Also known as: CHOLESTEROL AND NASH

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/585411]

Researchers: Prof Geoffrey Farrell (Principal investigator) ,  The Australian National University (Managed by)

Brief description Fatty liver is present in 15-30% of Australians, related to obesity, diabetes and heart attack. Two-thirds of cases reverse easily. The remainder evolve to non-alcoholic steatohepatitis (NASH), liver damage that can lead to cirrhosis and liver failure. This research seeks to find out why some cases of fatty liver lead to NASH, and whether cholesterol that accumulates in the livers of mice with NASH is what causes that damage. If so, we will find new ways to treat NASH by diet or drugs.

Funding Amount $AUD 533,541.03

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857