Mechanisms underlying the efficacy of bariatric surgery – insights from rat models of sleeve gastrectomy and the adjustable gastric band [ 2018 - 2021 ]

Research Grant

Researchers: Prof Brian Oldfield (Principal investigator) ,  Dr Paul Burton ,  Prof Wendy Brown

Brief description Bariatric surgery is the only effective treatment for morbid obesity. In order to better understand the mechanistic bases of two such procedures, the adjustable gastric band and sleeve gastrectomy, we have developed rodent models. Here we use these models to better understand the physiology and pathophysiology of these surgeries and extend these findings to inform part of a RCT aimed at identifying the basis for effective joint surgical and medicinal treatments of obesity.

Funding Amount $AUD 880,630.60

Funding Scheme Project Grants

Notes Standard Project Grant