Mechanisms underlying the effects of retinoic acid receptor gamma in haemopoiesis and bone homeostasis [ 2008 - 2010 ]

Research Grant

Researchers: A/Pr Louise Purton (Principal investigator)

Brief description My recent studies have demonstrated that a model of vitamin A deficiency results in impaired blood cell production and contributes to a blood cell disorder that can progress to leukaemia. There are also reduced numbers of blood stem cells (which give rise to all blood cells) and bone (which helps to regulate blood cell production) in this mouse model. In these studies I seek to understand more on how vitamin A deficiency causes these defects, which may lead to better treatment of such diseases.

Funding Amount $AUD 366,801.08

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF