Mechanisms of neurodegeneration in TDP-43 proteinopathies: frontotemporal dementia and amyotrophic lateral sclerosis [ 2012 - 2017 ]

Also known as: Investigating mechanisms of dementia and motor neuron disease

Research Grant

[Cite as]

Researchers: Dr Adam Walker (Principal investigator)

Brief description Dementia and motor neuron disease (MND) are both neurodegenerative diseases which have devastating impacts on patients and their families. My research investigates the biochemical mechanisms involved in these diseases. Pathology in the nervous system of dementia and MND patients contains a protein called ‘TDP-43’, but it remains unknown how this causes disease. This project will therefore explore the effects of TDP-43 malfunction, which will provide insight into potential therapeutic strategies.

Funding Amount $AUD 321,495.63

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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