grant

Mechanisms of islet graft rejection and acceptance [ 2011 - 2014 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1012522]

Researchers: Prof Barbara Fazekas De St Groth (Principal investigator)

Brief description Islet grafts offer diabetic patients the promise of a return to insulin-independence. In this project we will study how natural regulatory T cells suppress islet graft rejection in a mouse model. We will determine where regulatory T cells interact with graft-rejecting T cells, and define the mechanisms used to mediate their suppressive effects. Our findings will aid in developing new ways to induce long-term acceptance of islet grafts without immunosuppressive drugs.

Funding Amount $AUD 602,501.52

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857