Mechanisms of beta-cell dysfunction in diabetes [ 2012 - 2014 ]

Research Grant

Researchers: A/Pr David Laybutt (Principal investigator)

Brief description Type 2 diabetes is a health crisis in Australia. In this project, we will investigate the mechanisms whereby high glucose and fat impair pancreatic beta-cell function leading to type 2 diabetes. We will establish how endoplasmic reticulum stress and the protein Id1 are linked with loss of beta-cell gene expression and function. The information gained will further our understanding of the basic mechanisms regulating insulin secretion and provide new therapeutic targets for diabetes treatment.

Funding Amount $AUD 713,965.94

Funding Scheme Project Grants

Notes Standard Project Grant