Mechanisms of alpha-hemolysin induced immunoevasion by Staphylococcus aureus [ 2012 - 2014 ]

Research Grant

Researchers: Prof Wolfgang Weninger (Principal investigator) ,  A/Pr Neville Firth ,  Dr Arby Abtin

Brief description S. aureus infections represent a serious global health problem. Currently, no vaccination is available demanding a better understanding of the immune response against this bacterium. We will test the hypothesis that S. aureus alpha-hemolysin represses the migration of innate immune cells to sites of cutaneous infection resulting in diminished immunity. Unraveling the mechanism behind this phenomenon will pave the way to better prophylactic and therapeutic measures against S. aureus infections.

Funding Amount $AUD 465,475.00

Funding Scheme Project Grants

Notes Standard Project Grant