grant

Mechanisms of activation of vascular afferent nociceptors to the gut [ 2010 - 2012 ]

Also known as: How painful stimuli are detected by sensory nerves in the gut

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/595969]

Researchers: Prof Simon Brookes (Principal investigator) ,  Prof Nicholas Spencer

Brief description We have recently identified the nerve fibres responsible for detecting pain from the gut. In this project we will study exactly how these nerve cells are activated by movements of the gut wall, by changes in blood vessel diameter and how this can be studied most efficiently We will use this information to develop simple preparations in which to study these sensory nerves in animal and adult tissue to test which drugs may affect their excitability and hence be useful in treating gut pain.

Funding Amount $AUD 542,890.16

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857