Mechanism of interaction of VWC domains and consequence for protein function [ 2009 - 2012 ]

Research Grant

Researchers: Prof Philip Hogg (Principal investigator) ,  Dr Christina Schroeder

Brief description More than 1000 proteins contain a type of module known as the VWC domain. These domains are discreet sections of the protein that are very important for how the protein works. Proteins containing this domain are involved in normal functioning of the human body and in diseases of the nervous system and blood, among others. The main function of the VWC domain is to link proteins together in complexes. How this is achieved is not known and is what we aim to discover.

Funding Amount $AUD 516,803.14

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant