grant

The mechanism of growth hormone receptor activation [ 2008 - 2010 ]

Also known as: How does growth hormone work ?

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/511120]

Researchers: Prof Michael Waters (Principal investigator) ,  Dr Michael Gorman

Brief description Growth hormone GH excess or deficit results in considerably shortened lifespan. While cardiovascular disease is a major element in this mortality, GH status has also been linked to kidney disease and diabetic retinopathy. Importantly, GH produced locally in breast cells and prostate cells transform s these cells, creating cancers. We aim to define how GH activates its receptor, to facilitate a GH antagonist which results from understanding how GH activates its cell surface receptor.

Funding Amount $AUD 679,500.67

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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