Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1010887]Researchers: A/Pr Katryn Stacey (Principal investigator) , Dr Tara Roberts
Brief description DNA in mammalian cells is in a structure known as the nucleus. Retroviruses such as HIV generate DNA outside the nucleus in the cytoplasm, and detection of DNA in the cytoplasm can lead to cell death, as a defence. All cells carry the remnants of ancient retroviruses in their nuclear DNA. These are normally inactive but may contribute to cancer when activated. This project investigates how normal cells die with cytoplasmic DNA, and whether a defect in this process promotes development of cancer.
Funding Amount $AUD 517,897.37
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1010887
- PURL : https://purl.org/au-research/grants/nhmrc/1010887
