Mechanism of action and targeting of RAGE in inflammation [ 2013 - 2015 ]

Research Grant

Researchers: Prof Philip Hogg (Principal investigator)

Brief description Humans have evolved defense and repair mechanisms to counteract threats such as tissue injury and infection. The immune system first must detect the potential life-threatening event and it does so by recognizing danger signals. RAGE is a key cell-surface receptor that recognises these danger signals. Despite its important role in health and disease our understanding of how RAGE works is very limited. We will discover how RAGE works and how to manipulate its function for new infection therapies.

Funding Amount $AUD 386,423.53

Funding Scheme Project Grants

Notes Standard Project Grant