grant

Manipulation of Haematopoietic stem cell niches to improve their clinical use [ 2009 - 2011 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/543706]

Researchers: A/Pr Ingrid Winkler (Principal investigator) ,  Prof Jean-Pierre Levesque

Brief description Haematopoietic stem cells (HSC) reside in adult bone marrow (BM) and make all blood and immune cells. HSCs can be damaged by chemotherapy leading to blood and BM failure. We have identified an adhesion molecule in the BM which regulates HSC behaviour. We anticipate that inhibiting this molecule will i) help minimise HSC damage during chemotherapy and ii) enhance the success of BM transplantation.

Funding Amount $AUD 434,883.15

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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