Male Chlamydia infections: The key role of macrophages in testicular dissemination and disrupted spermatogenesis [ 2018 - 2022 ]

Research Grant

Researchers: Prof Kenneth Beagley (Principal investigator) ,  A/Pr Tim Dargaville ,  Dr Alison Carey ,  Prof Eileen Mclaughlin

Brief description Male partners of couples seeking IVF, who are seropositive for Chlamydia, indicating a prior infection, often have significantly impaired sperm quality (reduced motility, increased DNA damage and abnormal sperm morphology). Our studies will define how Chlamydia are transported to the testis from the penis and how chronic chlamydial infection in the testis disrupts sperm development. We will also develop new antibiotic delivery systems to improve treatment of male chlamydial infections.

Funding Amount $AUD 880,622.48

Funding Scheme Project Grants

Notes Standard Project Grant