Major Histocompatibility Complex (MHC) Genetics of Ankylosing Spondylitis [ 2009 - 2011 ]

Research Grant

Researchers: Prof Matthew Brown (Principal investigator) ,  Prof David Evans ,  Prof Huji Xu

Brief description Ankylosing spondylitis (AS) is the prototypic condition of a group of types of inflammatory arthritis called 'seronegative spondyloarthropathies'. These conditions are the most common form of inflammatory arthritis in white populations and occur worldwide. One third of the risk of developing AS is determined by genes within a region called the 'major histocompatibility complex' (MHC), in addition to the gene HLA-B27, the main gene causing AS. We aim to identify the remaining MHC genes.

Funding Amount $AUD 568,612.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant