Macrophages: a therapeutic target in peritoneal dialysis-induced fibrosis? [ 2011 - 2013 ]

Research Grant

Researchers: Prof Julie Campbell (Principal investigator) ,  Dr Barbara Rolfe ,  Prof David Johnson ,  Prof Ming Wei

Brief description Fibrosis (scar tissue) in the abdominal cavity is a common side-effect of peritoneal dialysis (a treatment for kidney failure), and results in a life-threatening loss of dialysis function. The cells causing the fibrosis are uncertain. This project asks: Are inflammatory cells (macrophages) the source of peritoneal scar tissue? What regulates the fibrotic process? Answers may lead to strategies to prevent fibrosis induced by peritoneal dialysis, abdominal surgery or other causes.

Funding Amount $AUD 593,888.23

Funding Scheme Project Grants

Notes Standard Project Grant