Macrophage Polarisation and Control of Pulmonary Inflammation. [ 2018 - 2021 ]

Research Grant

Researchers: Prof Jennifer Stow (Principal investigator) ,  Dr Emmanuelle Fantino ,  Prof Peter Sly

Brief description As key immune cells, macrophages are polarised to phenotypes that turn inflammation on or off. In cystic fibrosis, defective macrophage polarisation enhances inflammation and prevents lung repair. We are defining the molecules and cellular pathways that control this process and identifying targets for existing drugs that can be used to reprogram macrophages and restore lung repair to improve patient outcomes.

Funding Amount $AUD 908,031.32

Funding Scheme Project Grants

Notes Standard Project Grant