Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/379615]Researchers: Prof Scott Ritchie (Principal investigator) , Prof Richard Russell
Brief description Dengue fever is a growing threat to human health in the tropics. In north Queensland, 11 dengue outbreaks have resulted in 985 confirmed cases since 2000. Furthermore, 2004 saw the emergence of severe disease, with 4 cases of dengue haemorrhagic fever resulting in at least one death in the Torres Strait. The current dengue managment plan employs methods to control larvae and adults of the mosquito vector, Aedes aegypti. Adult control consists of spraying dark, protected areas inside houses and buildings with a residual pyrethroid insectcide. However, this method is laborious and exposes residents and the environment to pesticide. Our research team, funded by NHMRC project grant no. 279401, has developed lure and kill methods to kill Ae. aegypti mosquitoes using traps. These traps are baited with chemicals that attract female dengue mosquitoes trying to bite (host-seeking traps; HSTs) or trying to lay eggs (lethal ovitraps; LOs). The use of traps to kill specific target insects is termed lure and kill strategy. This strategy reduces the amount of pesticide used by 1000X, and are twice as fast to employ than house spraying. We are seeking funding to conduct a series of field trials to provide proof of concept that the lure and kill strategy will rapidly reduce populations of Ae. aegypti and thus stop dengue transmission. These trials will be conducted in the Cairns area. We will also trial a biodegradable lethal ovitrap that could be put into yards without having to return to retrieve the trap. The trap would simply biodegrade after 4 weeks, and thus pose no threat to become a mosquito breeding site once the pesticide had become ineffective. A biodegradable trap would be especially useful in the Torres Strait where return visits are costly and time consuming. Finally, we propose to trial a new paper strip device that emits vapors of the pyrethriod insecticide metofluthrin, shown to repel mosquitoes for weeks, to set in dengue case houses.
Funding Amount $AUD 318,621.40
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 379615
- PURL : https://purl.org/au-research/grants/nhmrc/379615