Is low dose amitriptyline more effective than placebo in the management of chronic, neuropathic low back pain? A double-blind, randomized, placebo-controlled trial with an economic evaluation [ 2012 - 2014 ]

Research Grant

Researchers: Dr Donna Urquhart (Principal investigator) ,  A/Pr Anita Wluka ,  Prof Andrew Forbes ,  Prof Malcolm Sim ,  Prof Maurits Van Tulder
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Brief description Chronic low back pain is a major public health problem in Australia. Antidepressants are a common treatment for low back pain, with physicians often prescribing them at low doses for the treatment of pain. However, the use of antidepressants for low back pain is unproven. We aim to perform a clinical trial to examine whether antidepressants are more effective than placebo in reducing pain and disability in patients with chronic low back pain.

Funding Amount $AUD 306,889.50

Funding Scheme Project Grants

Notes Standard Project Grant