A longitudinal neuroimaging study investigating reorganisation of cerebellar-cerebral networks in Friedreich ataxia [ 2013 - 2017 ]

Research Grant

Researchers: Prof Nellie Georgiou-Karistianis (Principal investigator) ,  Dr Andrew Churchyard ,  Dr Louise Corben ,  Prof Gary Egan ,  Prof Martin Delatycki

Brief description Friedreich ataxia (FRDA) causes debilitating motor and cognitive deficits. We propose a longitudinal multi-modal magnetic resonance (MR) imaging study to measure different types of tissue in the brain in this disease. We seek to understand how the brain reorganises itself due to cell loss in the spinal cord, cerebellum and cerebral cortex. This study will establish sensitivity of a range of MR imaging measures as potential biomarkers for use in large multi-centre drug trials in this disease.

Funding Amount $AUD 816,908.86

Funding Scheme Project Grants

Notes Standard Project Grant