Local cardiac sex steroids - new therapeutic targets [ 2016 - ]

Research Grant

Researchers: Prof Leanne Delbridge (Principal investigator) ,  Dr James Bell ,  Prof Jonathan Kalman ,  Prof Stephen Harrap

Brief description The sex hormones, estrogen and testosterone, are implicated in susceptibility to heart diseases - the timing and type of disease development is different for women and men. The mechanisms for this are unknown. In this project we investigate the synthesis and breakdown of these hormones in the heart and determine how local hormone levels may affect heart muscle cell survival and function. The aim is to find ways of adjusting hormone balance to optimize protection when the heart is under stress.

Funding Amount $646,994.00

Funding Scheme Project Grants

Notes Standard Project Grant