Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/491256]Researchers: Dr Heidi Peters (Principal investigator)
Brief description We propose to investigate the role of liver cell transplantation (LCT) for the therapy of inherited liver-based metabolic diseases using a methylmalonic aciduria (MMA) mouse model. LCT provides an exciting alternative to whole organ transplantation. Initially it was considered liver cells would be immunopriviledged. This has not proven to be the case. Immune modulation will be important. We will also examine immune modulation using antibodies to optimise longterm survival of allogeneic cells.
Funding Amount $AUD 444,143.91
Funding Scheme NHMRC Project Grants
Notes New Investigator Grant
- nhmrc : 491256
- PURL : https://purl.org/au-research/grants/nhmrc/491256
