Lipotoxicity, mitochondrial dysfunction and the pathogenesis of heart failure [ 2012 - 2017 ]

Also known as: Do fatty acids poison the heart’s energy generation?

Research Grant

[Cite as]

Researchers: A/Pr Aaron Sverdlov (Principal investigator)

Brief description Heart failure (HF) is the most common basis for hospitalisation or cardiac death despite improved treatment options. Impaired energy generation within heart muscle is important in causing HF, but little is known about this process. I plan to investigate the effects of fatty acid overload, as occurs in obesity and/or diabetics, on cardiac energy generation. Then, I'll explore the benefits of limiting fatty acids during heart surgery, in order to help in understanding the causes of HF, and the benefits of new, energy-conserving treatments

Funding Amount $AUD 454,358.10

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

Click to explore relationships graph
Viewed: [[ro.stat.viewed]]