How lipids affect signalling efficiencies in T cells [ 2012 - 2014 ]

Research Grant

Researchers: Prof Katharina Gaus (Principal investigator) ,  Dr Jeremie Rossy

Brief description A high fat diet can compromise the function our immune system. This project examines how lipids affect T cells. We propose that T cells from mice on a high fat diet can no longer respond to an immune challenge because the signalling processes that lead to activation are deregulated. We have established a new microscopy technique that allows us to measure the efficiency of signalling processes. We will use this method to identify which lipids contribute the most to T cell deregulation.

Funding Amount $AUD 472,882.39

Funding Scheme Project Grants

Notes Standard Project Grant