Lipid rafts, amyloid neurotoxicity and Alzheimer's disease [ 2006 - 2008 ]

Research Grant

Researchers: Prof David Small (Principal investigator) ,  Dr Steven Petratos ,  Prof Marie-Isabel Aguilar

Brief description Alzheimer's disease is the major cause of dementia in the elderly. Individuals with Alzheimer's disease exhibit a slow decline in cognition which usually results in prolonged institutionalisation. This creates an enormous burden on society. The project aims to identify mechanisms which cause Alzheimer's disease. Specifically, it will examine how a component of the brain, known as the amyloid protein, contributes to nerve cell degeneration. It is hoped that by identifying these mechanisms, new targets for drug development will be found.

Funding Amount $AUD 318,267.61

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant