Linking genomics of Burkholderia pseudomallei to melioidosis: diversity of clinical manifestations, changing epidemiology and microevolution in chronic carriage. [ 2013 - 2015 ]

Research Grant

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Researchers: Prof Bart Currie (Principal investigator) ,  A/Pr Apichai Tuanyok Dr Derek Sarovich Dr Erin Price Dr Mirjam Kaestli
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Brief description The Darwin Prospective Melioidosis Study has documented 761 cases since 1989, with 102 fatalities. This study has led to improved therapy and public health initiatives. New technology to sequence whole bacterial genomes provides an opportunity to determine why urban melioidosis is increasing and to analyse this unique 22+ year set of bacteria and their linked patient data to find the important bacterial virulence factors, forming a foundation for future diagnostics, therapeutics, and vaccines.

Funding Amount $AUD 602,769.63

Funding Scheme Project Grants

Notes Standard Project Grant

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