Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/628643]Researchers: Prof Leanne Delbridge (Principal investigator) , Prof Stephen Harrap
Brief description An enlarged heart at maturity is a major risk factor. The goal of this project is to understand how cardiac growth abnormality in the neonate contributes to adult growth pathology. We have recently discovered that a type of stress-triggered cell death (autophagy) is increased in rodent neonatal hearts which later become enlarged, and that this cell death is regulated by the hormone angiotensin II. We will study the mechanisms involved to identify intervention opportunities to normalize growth.
Funding Amount $AUD 524,013.18
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 628643
- PURL : https://purl.org/au-research/grants/nhmrc/628643
